A proven way to treat skin cancer — without surgery.

Now offering GentleCure^TM image-guided SRT, a non-surgical skin cancer treatment that’s safe, effective, and done right in our office.

If you’ve been diagnosed with basal cell or squamous cell carcinoma, there’s a treatment option that doesn’t involve cutting, stitching, or reconstruction. GentleCure is a gentle, surgery-free treatment that uses advanced imaging and low-energy radiation to treat skin cancer without damaging surrounding healthy tissue.

Find out more about:

Trusted dermatologic care in Decatur and Madison Alabama.

-Specializing in skin cancer
-Dermatologic – cosmetic surgeon
-Fellowship training
-Board certified in dermatology
-Over 10 years experience in SRT

-Articles published nationally and
internationally – in medical journals
-First to perform mohs surgery
in North Alabama

Welcome to the dermatology practice of Dr. Angelo Mancuso, a board-certified dermatologist serving Decatur and Madison, Alabama for over 40 years. A graduate of the Philadelphia College of Osteopathic Medicine, Dr. Mancuso brings deep expertise in both medical and surgical dermatology, offering advanced care for skin cancer, acne, eczema, psoriasis, and other complex skin conditions. He is known throughout the region for his precise surgical skills, long-standing patient relationships, and straightforward, results-driven care. With offices in two convenient locations and a wide range of accepted insurance plans—including Medicare and Medicaid—Dr. Mancuso is proud to offer accessible, evidence-based skin care to individuals and families across North Alabama.

When it comes to treating nonmelanoma skin cancer—like basal cell and squamous cell carcinoma—there’s no one-size-fits-all approach. At our practice, Dr. Angelo Mancuso, offers two trusted treatment paths: Mohs surgery and Image-Guided Superficial Radiation Therapy (SRT) using the GentleCure process.

Both options are backed by clinical research and used by dermatologists across the country. The best choice depends on your specific diagnosis, location of the cancer, medical history, and personal preference.

Mohs Surgery:

A surgical procedure that removes the skin cancer layer by layer under a microscope
Typically performed in-office with local anesthesia
Offers immediate results and high cure rate

Image-Guided SRT (GentleCure):

A non-surgical treatment that uses low-energy X-rays to target the cancer site
Offers immediate results and high cure rate
Ultrasound imaging is used at each visit to monitor treatment progress
No cutting, no stitches, no scarring
Ideal for patients who are not candidates for surgery or prefer a gentler, non-invasive option
Covered by Medicare and most insurance

A surgery-free skin cancer treatment done in our office.

Dr. Mancuso offers a non-invasive treatment for nonmelanoma skin cancer, including basal cell carcinoma and squamous cell carcinoma.

This treatment is called Image-Guided Superficial Radiation Therapy (SRT) — a safe, effective alternative to Mohs or traditional surgery.

It works by delivering low-energy X-rays directly to the cancer site, guided by real-time ultrasound imaging that helps ensure accuracy with each session. There are no incisions, no stitches, and minimal disruption to your daily life.

Important: This treatment is not appropriate for melanoma.

Want to speak with someone now?

If you have questions about treatment, insurance, or whether this option is right for you, reach out to our office anytime. We’re here to walk you through every step.

Addresses

Southern Dermatology Center PC
Decatur Med-Surg Clinic
Address: 2828 Hwy 31 S #105,
Decatur, AL 35603
Phone: (256) 351-9996

Southern Dermatology Center PC
Madison
540 Hughes Rd Ste 3.
Madison, AL 35758.
Phone: (256) 351-9996

Before

During

After

Actual ultrasound screens

We track your treatment progress at every visit.

Our Board Certified RTT uses the Image-Guided Superficial Radiation Therapy (SRT) machine to deliver doses of low energy X-rays to the cancer spot, killing the skin cancer cells while preserving the healthy tissue and cells around it.

GentleCure is the only skin cancer treatment that uses ultrasound images so you can see your skin cancer shrink at each visit until it is cured. These images help your RTT and dermatologist tailor each treatment to work exactly for your cancer.

GentleCure testimonials

No cutting or stitches

Covered by most insurance

In-office care — no hospital

98% to99% effective for basal and squamous cell carcinoma

Clinically proven results, backed by research.

A peer-reviewed study published in Oncology and Therapy in 2021 found that Image-Guided SRT was 99% effective in treating basal and squamous cell carcinoma across more than 1,600 patients.

Because of its success rate and precision, Image-Guided SRT is covered by Medicare and most major insurance providers. It’s a trusted, research-supported option for eligible patients who want to avoid surgery.

Yu L, et al. Oncol Ther.
2021;9(1):153-166. Retrospective chart review evaluating LC rates of 1632 patients with 2917 stage 0-II carcinomas

Mohs Surgery for Skin Cancer Treatment

What Is Mohs Surgery?

Mohs micrographic surgery is a specialized surgical technique used to treat nonmelanoma skin cancers, particularly basal cell carcinoma and squamous cell carcinoma. It is considered the gold standard for removing certain skin cancers, especially those located in sensitive or high-visibility areas such as the face, ears, nose, scalp, and hands. The goal of Mohs surgery is to completely remove the cancer while preserving as much healthy tissue as possible—making it ideal for cosmetically or functionally important areas.

How the Mohs Process Works

Unlike traditional excision methods, Mohs surgery is performed in stages, all in one visit:

1. Local anesthesia is used to numb the treatment area.
2. Dr. Mancuso removes a thin layer of visible cancerous tissue.
3. The tissue is immediately examined under a microscope in an on-site lab.
4. If cancer cells are still present at the edges (“margins”), the process is repeated only in those areas.
5. Once all margins are clear, the site is closed or allowed to heal naturally, depending on its location and size.

This process may be repeated several times in one visit until the cancer is fully removed—giving Mohs its reputation for precision and high cure rates for basal cell carcinoma of 98% and 96% to 98% squamous cell carcinoma.

Dr. Mancuso’s Experience with Mohs

With over 40 years of clinical experience in dermatologic surgery, Dr. Angelo Mancuso, brings skill, precision, and a steady hand to every Mohs procedure. Patients trust him not only for his surgical expertise, but also for his ability to explain each step clearly and ensure comfort throughout the process.

Is Mohs Surgery Right for You?

Dr. Mancuso will evaluate your specific diagnosis, location of the lesion, overall health, and treatment history to determine if Mohs surgery is the most appropriate option. In some cases, non-surgical alternatives like Image-Guided SRT like GentleCure may also be considered.

Ready to Learn More?

Call our office today at 256-351-9996 or fill out our contact form to schedule a consultation and learn whether Mohs surgery is the right approach for your skin cancer treatment.

We’re here to help.

If you have questions about treatment, insurance, or whether this option is right for you, reach out to our office anytime. We’re here to walk you through every step.

Addresses

Southern Dermatology Center PC
Decatur Med-Surg Clinic
Address: 2828 Hwy 31 S #105,
Decatur, AL 35603
Phone: (256) 351-9996

Southern Dermatology Center PC
Madison
540 Hughes Rd Ste 3.
Madison, AL 35758.
Phone: (256) 351-9996